MersV1, Main, Exploration, bibRecord, 000F63

Vaccine Development Against Middle East Respiratory Syndrome

Identifieur interne : 000F63 ( Main/Exploration ); précédent : 000F62; suivant : 000F64

Vaccine Development Against Middle East Respiratory Syndrome

Auteurs : Hai Yen Lee [Malaisie, États-Unis] ; Mun Peak Nyon [Malaisie, États-Unis] ; Ulrich Strych [États-Unis]

Source :

Current Tropical Medicine Reports [ 2196-3045 ] ; 2016.

RBID : PMC:7099997

Abstract

Various types of vaccines are under pre-clinical and clinical development to address the recent appearance of Middle East respiratory syndrome or MERS, an emerging infectious disease that has already caused over 600 deaths and remains a threat to world health. The causative agent for this respiratory disease is a member of the betacoronavirus genus, phylogenetically closely related to the SARS coronavirus that caused an international health emergency in 2002. With lessons learned from the outbreak of severe acute respiratory syndrome, and with undeniable technological advances, vaccine development against MERS was initially fast-paced and has produced several DNA and protein vaccine candidates with promising results during early pre-clinical testing. At least one vaccine candidate has even entered first-in-humans clinical trials now. With the number of MERS cases declining though and other infectious diseases attracting increased attention, the question remains, whether, similar to the situation after the SARS pandemic, vaccine development is halted or remains the priority it rightfully should.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7099997

DOI: 10.1007/s40475-016-0084-0
PubMed: 32226714
PubMed Central: 7099997

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p id="Par1">Various types of vaccines are under pre-clinical and clinical development to address the recent appearance of Middle East respiratory syndrome or MERS, an emerging infectious disease that has already caused over 600 deaths and remains a threat to world health. The causative agent for this respiratory disease is a member of the betacoronavirus genus, phylogenetically closely related to the SARS coronavirus that caused an international health emergency in 2002. With lessons learned from the outbreak of severe acute respiratory syndrome, and with undeniable technological advances, vaccine development against MERS was initially fast-paced and has produced several DNA and protein vaccine candidates with promising results during early pre-clinical testing. At least one vaccine candidate has even entered <italic>first-in-humans</italic>
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Serveur d'exploration MERS

Vaccine Development Against Middle East Respiratory Syndrome

Vaccine Development Against Middle East Respiratory Syndrome

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Abstract

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